| 梁晓春,郭赛珊,王香定,孙懿珍,沈瑛,姚富英,谢明智,申竹芳,刘海帆,刘京.金芪降糖片治疗气阴两虚火旺型糖尿病临床及实验研究[J].中国中西医结合杂志,1993,(10):587-590,579 |
| 金芪降糖片治疗气阴两虚火旺型糖尿病临床及实验研究 |
| Clinical and Experimental Study on Effect of Jin-Qi-Tang-Pian on Qi-Yin Deficiency and Hyperactivity of Fire Type of Diabetes Mellitus |
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| DOI： |
| 中文关键词: 金芪降糖片 气阴两虚火旺 血糖 红细胞超氧化物歧化酶 脂质过氧化 胰岛素水平 |
| 英文关键词:Ji-Qi-Jiang-Tang-Pian blood sugar diabetes mellitus |
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| 中文摘要: |
| 本研究报告应用金芪降糖片治疗气阴两虚火旺型糖尿病患者40例的临床疗效及动物实验研究。结果表明金芪降糖片对糖尿病患者及实验性糖尿病动物均有明显降低血糖效果,血清胰岛素水平有下降的趋势。临床气阴两虚火旺的八个主要症状明显改善。并可提高患者ESOD水平,使实验性大鼠肝匀浆MDA水平下降,ESOD/MDA比值升高,提示该药不仅能很好地控制血糖,还可提高机体消除自由基的能力,抑制脂质过氧化作用。 |
| 英文摘要: |
| The purpose of this study was to verify the effect of Jin-Qi-Jiang-Tang-Pian (JQJTP) on fastingblood glucose (FBG), postcibal blood glucose (PBG), total cholesterol (TC), triglycerides (TG),acetylcholine esterase (AchE), insulin, RBC-superoxide dismutase (RBC-SOD) and malondealdehyde(MDA). Efficacy was observed in 40 cases of diabetes mellitus. 20 cases administered with Yu-QuanPian ( YQP) were taken as control. Each group took drugs for two months. After treatmentwith Jin-Pi-Jiang-Tang-Pian, FBG、PBG、AchE were apparently dropped and RBC-SOD increased.as compared with patients of the YQP group (P< 0.03-0.01). and major symptoms of diabetes wereimproved. In experimental study, model rats suffering from diabetes induced by alloxan wereobserved, the rats’ blood sugar level above 11.1 mmol/L, were chosen for observation. These ratswere divided into JQJTP group, YQP group and control group. It was found that JQJTP was ableto lower blood sugar, TG and MDA (P< 0.05-0.001) significantly, with a increase of the SOD/MDA, as compared with those of patients of the control groups. |
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