活血化瘀经典古方对家兔血小板聚集性的影响

作者	单位
葛争艳	中国中医研究院西苑医院
林成仁	中国中医研究院西苑医院
周亚伟	中国中医研究院西苑医院
王敏	中国中医研究院西苑医院
李连达	中国中医研究院西苑医院

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中文摘要:

本实验在体外用花生四烯酸诱导家兔血小板聚集，观察８个活血化瘀古方对血小板聚集性的影响。结果：各古方均有不同程度的抑制血小板聚集作用，其中以膈下逐瘀汤、身痛逐瘀汤和少府逐瘀汤作用最强，其次是补阳还五汤和血府逐瘀汤。提示：此８个活血化瘀古方的抑制血小板聚集作用可能是治疗血瘀证的机制之一。

英文摘要:

Arachidonic acid can induce platelet aggregation in rabbits in vitro. The experimental model was designed to observe inhibitory effect of 8 classical recipes of activating blood circulation to remove the stasis on platelet aggregation in vitro. The results showed that each one of 8 classical recipes has inbibitory effect on platelet aggregation in vitro in various degree.Among them,Gexia Zhuyu Tang(GZT),Shentong Zhuyu Tang(SZT)and Shaofu Zhuyu Tang(SFZT) were more effective.The results suggested that inhibitory effect of platelet aggregation produced by 8 classical recipes might be one of mechanisms of blood stasis treatment.

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