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沈迪,沈霖,王爱莲,崔国惠,魏文宁,刘仲萍,杨锐.消瘀片治疗新型血小板聚集功能缺陷症的临床研究[J].中国中西医结合杂志,1994,(10):589-591
消瘀片治疗新型血小板聚集功能缺陷症的临床研究
Effect of Xiaoyu pian on New Platelet Aggregation Defect
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DOI:
中文关键词:  新型血小板聚集功能缺陷症  消瘀片  刺参酸性粘多糖  血小板聚集
英文关键词:new platelet aggregation defect  Xiaoyu pian  platelet aggregation Stichopus Japanicus Slenka acid mucopolysaccharide
基金项目:
作者单位
沈迪 同济医科大学附属协和医院 
沈霖 同济医科大学附属协和医院 
王爱莲 同济医科大学附属协和医院 
崔国惠 同济医科大学附属协和医院 
魏文宁 同济医科大学附属协和医院 
刘仲萍 同济医科大学附属协和医院 
杨锐 同济医科大学附属协和医院 
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中文摘要:
      本研究采用中药消瘀片治疗新型血小板聚集功能缺陷症72例,并与维生素C、P加安络血组65例作对照,进行临床症状和血小板聚集功能的疗效比较。结果:显效率:中药组为87.5%,对照组为35.4%;两组血小板聚集缺陷恢复率分别为91.8%与11.8%;停药6个月后随访的复发率分别为30.8%与82.1%。两组间的差异均非常显著(P<0.0l)。结果表明:消瘀片有调节止血功能和血小板聚集功能,值得临床推广应用。
英文摘要:
      The Xiaoyu pian(XYP, mainly consisted of prunus persica, Carthamus tinctorius, Glycyrrhiza uralensis, etc) was used to treat patients with new platelet aggregation defect. Patients were divided into 2 groups, the TCM group (72 cases) treated with XYP and the control group (65 cases) treated with vitamin C and P and/or adrenosem for at least 3 months. The results showed that marked effective rate was 87.5% in TCM group and 35.4% in control group (x2=39.7, P<0.01); the recovery rate of platelet was 91.8% in the former and 10.3% in the latter (x2=71.4, P<0.0l); the recurrence rate of follow-up(6 months after treatment) was 30.8% in the former and 82.1% in the latter (x2= 19.2, P<0.01). The difference between two groups was very significant. The results suggested that XYP could regulate the hemostatic action and the platelet aggregation function. It is worth while to use XYP as an hemostatic clinically.
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