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林求诚,叶盈,方素钦,王耀华,沈宗国.真菌降脂素治疗脂质代谢紊乱的临床研究[J].中国中西医结合杂志,1995,(5):281-283
真菌降脂素治疗脂质代谢紊乱的临床研究
Clinical Study on Fungus Lipid-Reducing Capsule in Regulating Lipometabolic Disorder
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DOI:
中文关键词:  真菌降脂素  脂质代谢紊乱  高胆固醇血症  高甘油三酯血症  低高密度脂蛋  白胆固醇血症
英文关键词:fungus lipid-reducing capsule  lipometabolic disorder  hypercholesteremia  hypertriglyceridemia  low-high density lipoprotein cholesterolemia
基金项目:
作者单位
林求诚 福建省中医药研究院 
叶盈 福建省中医药研究院 
方素钦 福建省中医药研究院 
王耀华 福建医学院附属第一医院 
沈宗国 福建省人民医院 
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中文摘要:
      140例患者随机分为真菌降脂素治疗组与山楂精降脂片对照组各70例,另设真菌降脂素扩大治疗组90例。结果:治疗组与对照组胆固醇(TC)、甘油三酯(TG)含量均明显下降,但治疗组下降的幅度大于对照组(P<0.05);HDL-C含量两组皆有上升,但治疗组上升的幅度大于对照组(P<0.05),提示本品的调脂疗效优于对照药物。治疗组高TC血症38例,显效16例,有效16例,总有效率84%;高TG血症56例,显效23例,有效24例,总有效率84%;低HDL-C血症26例,显效12例,有效6例,总有效率69%。治疗组的血液流变学指标得到明显改善。中医证候疗效表明,真菌降脂素有健脾祛湿、滋养肝肾的功效。结合安全性观测,表明该药是有效而安全的调脂药物。
英文摘要:
      The patients with lipometabolic disorder were randomly divided into control group(70 cases),Fungus.Lipid-reducing Capsule(FLC)treated group(70 cases),augmented treated group (90cases).The results shown that:(1)TC and TG were reduced markedly in all three groups. The reducing extent in the treated group was greater than that in the control group (P<0.01).HDL-C was increased markedly in all three group.The increasing extent in the treated group was greater than that in the control group(P<0.05).These results indicated that the effectiveness of FLC was higher than that of control drug in the treatment of hyperlipidemia.(2)FLC had obvious effect in improving hemorheology indexes. (3) The therapeutic effect of TCM Syndrome-tape indicated that FLC could activate the Spleen, remove Dampness and nourish the Liver and Kidney.
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