大蒜素对急性脑梗塞患者外周血白细胞变形性的影响

作者	单位
毛建生	北京中日友好医院
史载祥	北京中日友好医院
庄逢源	北京中日友好医院
张久亮	北京中日友好医院
张铁忠	北京中日友好医院
李海聪	北京中日友好医院
杜金行	北京中日友好医院

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中文摘要:

为验证大蒜素对急性脑梗塞的疗效，采用核孔滤膜法，系统观察了５３名健康人及３３例经ＣＴ确诊的急性脑梗塞患者治疗前、后外周血白细胞滤过指数。结果发现，脑梗塞急性期外周血白细胞滤过指数明显升高，经大蒜素治疗后，在症状改善同时白细胞滤过指数明显降低。与此同时，全血流变学指标也有改善。从而提示大蒜素可以有效地改善白细胞变形性及全血流变性。

英文摘要:

To prove the effect of Allitridi in treating acute cerebral infarction,millipore membrane filter technique was adopted in systematically observing the blood rheology and the peripheral WBC filter index of 53 healthy subjects and that of 33 patients before and after treatments,who suffered from acute cerebral infarction and were confirmatorily diagnosed through CT.As a result,the filtered index of peripheral WBC during the acute period of cerebral infarction rose significantly(6.1397±4.4602),and the difference was significant compared with that of the healthy subjects(0.8651 ±0.4603,P<0.01).Having been treated with Allitridi,the patients,symptoms improved and at the same time the filtered index of WBC lowered markedly(1.6261±1.3472).The conditions of the patients before and after treatments were obviously different(p<0.01).And also the index of the whole blood rheology improved significantly.Therefore,it denoted that Allitridi could effectively improve the WBC deformation and the whole blood rheology as well,and alleviate the clinical symptoms.

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