刘新槐,任映,宋崇顺,师园,高金福,郭志强,杨振业.抗脑血栓注射液抗实验性动脉血栓作用及其机理初探[J].中国中西医结合杂志,1995,(7):424-425 |
抗脑血栓注射液抗实验性动脉血栓作用及其机理初探 |
Study of Anti- Cerebral Thromboembolism lnjection’s Activity on Experimental Arterial Thrombosis and Its Therapeutical Mechanism |
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DOI: |
中文关键词: 抗脑血栓注射液 血液流变学 血栓形成 |
英文关键词:Anti-Cerebral Thromboembolism Injection hemorheology thrombosis |
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中文摘要: |
为了解抗脑血栓注射液抗实验性动脉血栓的作用,用Cattaneo制作动脉血栓动物模型进行观察。结果耳静脉滴注抗脑血栓注射液后,模型动物的血栓重量、凝血酶原时间延长程度、全血粘度降低程度和血栓素B2(TXB2)浓度均较生理盐水对照组有所降低,P均<0.05~0.01。认为抗脑血栓注射液的抗血栓作用是通过降低全血粘度和TXB2浓度,从而抑制血小板的聚集和释放反应的结果。 |
英文摘要: |
Anti-Cerebral Thromboembolism Injection(ACTI),applied intravenously in Cattaneo’s animal model of arterial thrombosis,could significantly reduce the weight of thrombus,blood viscosities, plasma TXB2 level and delay the prothrombin time,compared to control group(P<0.05).From this trial,it was indicated that ACTI’s reducing thrombosis action was the result of inhibiting aggregation and releasing of platelets through reducing whole blood viscosities and TXB2 level. |
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