胆复康冲剂治疗胆囊炎、胆石症的临床与实验研究

为探讨胆复康冲剂治疗胆囊炎、胆石症的临床疗效，非手术胆复康冲剂治疗组２００例，以Ｂ超为主的检查作治疗前后对比。结果表明：２００例中治愈４８例（２４％），显效７６例（３８％），好转７０例（３５％），无效６例（３％），总有效率９７％。对胆囊结石直径＜０．５ｃｍ及泥沙样结石，经胆囊造影有收缩功能的排石率达６２％。手术后胆复康治疗组５０例，治愈２８例（５６％）．显效１８例（３６％），好转２例（４％），无效２例（４％），总有效率９６％。手术后对照组５０例，治愈８例（１６％），显效１２例（２４％），好转１５例（３０％），无效１５例（３０％），总有效率７０％。手术后治疗组与手术后对照组总有效率比较有显著性差异（Ｐ＜０．０５）。实验研究证明：实验组豚鼠肝胆汁的流量为３．７±０．４ｍｌ／ｈ，显著高于对照组（２．７±０．１ｍｌ／ｈ），Ｐ＜０．０５。实验组豚鼠的成石率（３２．４％）明显低于对照组（９３．８％），Ｐ＜０．０１，说明实验组豚鼠形成的胆石通过胆道内冲洗作用被排出。

英文摘要:

In order to evaluate the clinical effect of Danfukang Granule (DFKG) in treating cholecystitis and cholelithiasis, 200 patients were treated with DFKG and observed with ultrasonography before and after treatment. Results showed 48 cases(24%) among the 200 patients were cured, 76(38%) were marked effective, 70(35%) were improved and 6(3%) ineffective, the effective rate being 97%.The lithagogue rate of cholelithiasis patients with diameter of gallstone <0.5 cm, or those with sandy stone was 62%. In 50 post-operative patients received DFKG treatment, 28(56%) were cured,18(36%) marked effective, 2(4%) improved and 2(4%) were ineffective, the total effective rate being 96%, while in the other 50 cases did not receive DFKG, the numbers were 8(16%), 12(24%),15(30%), 15(30%) and 70% respectively. The difference of total effective rate between the two groups were significant(analyzed by x2 test, P<0.05). Experimental study-showed that the flow of hepatic bile in experimental group of guinea-pig was 3.7±0.4ml/h, which was singnificantly higher than that of control group(2.7±0.1ml/h), P <0.05. The bile stone formation rate in experimental group was 32.4%, which was markedly lower than that of control group(93.8), P<0.01, suggesting the bile stone formed in experimental guinea-pigs could be evacuated by the rinsing effect of DFKG.

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