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时毓民,张亦群,方善庆.镇咳灵口服液治疗儿童咳嗽的临床及实验研究[J].中国中西医结合杂志,1996,(7):390-393
镇咳灵口服液治疗儿童咳嗽的临床及实验研究
Clinical and Experimental Studies of Zhenkeling Oral Liquor on Treatment Infantile Cough
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DOI:
中文关键词:  镇咳灵口服液  咳嗽    动物实验
英文关键词:Zhenkeling oral liquor  cough  sputum  animal experiment
基金项目:
作者单位
时毓民  
张亦群  
方善庆  
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全文下载次数: 1038
中文摘要:
      将170例咳嗽患儿随机分为两组,镇咳灵口服液组(镇咳灵组)120例,小儿止咳化痰糖浆组(对照组)50例。结果镇咳灵组及对照组总有效率分别为96.7%、56.0%。愈显率分别为80.8%、18.0%(P均<0.001)。动物实验结果表明,镇咳灵口服液有明显的镇咳、祛痰及平喘作用,并有抗炎及抗菌作用。急性及慢性毒性实验表明该药无任何毒副作用。
英文摘要:
      One hundred and seventy children with cough were divied into two groups at random.120 patient were treated with Zhenkeling oral liquor(ZKL group).The other 50 children were given pectoral syrup(control group).The results showed that the total effective rates of ZKL group and control group were 96.7% and 56. 0% respectively,and the markedly effective rates were 80.8%,18.0% respectively(P<0.001).Animal experiments indicated Zhenkeling has the effect of relieving cough,reducing sputum and ameliorating asthma,their antibiotic and anti-inflammatory effects were discovered too.The dosage of Zhenkeling was 100 times as clinical dose in acute toxicity test and the dosage was 32,16,8 times as clinical dose in long term toxicity test respectively.No adverse action was found in these experiments.
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