| 喻嵘,王东生,周衡,吴勇军.茵陈五苓散治疗高脂蛋白血症的临床与实验研究[J].中国中西医结合杂志,1996,(8):470-473 |
| 茵陈五苓散治疗高脂蛋白血症的临床与实验研究 |
| Clinical and Experimental Study on Effects of Yinchen Wuling Powder in Preventing and Treating Hyperlipoproteinemia |
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| DOI： |
| 中文关键词: 茵陈五苓散 高脂蛋白血症 血脂 过氧化脂质 谷胱苷肽过氧化物酶 |
| 英文关键词:Yinchen Wuling powder hyperlipoproteinemia blood lipid lipid peroxidation glutathione peroxidase |
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| 摘要点击次数: 1585 |
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| 中文摘要: |
| 以经方茵陈五苓散治疗高脂蛋白血症３０例，显效率６３．３％，总有效率９３．３％。同时采用绞股蓝总甙对照治疗３０例，显效率２０．０％，总有效率８６．７％。治疗组疗效明显优于对照组（Ｐ＜０．０１）。动物实验表明：该方预防及治疗给药均能显著地抑制高脂血症模型大鼠血清总胆固醇、甘油三酯、低密度脂蛋白浓度的升高，以及抑制低密度脂蛋白与高密度脂蛋白比值的升高（Ｐ＜０．０１）。此外，本方还具有显著地抗氧化作用，能使血中过氧化脂质含量降低，而谷胱苷肽过氧化物酶活性增强。 |
| 英文摘要: |
| Sixty cases with hyperlipoproteinemia(30 cases each group) were observed. The total effective rate of the treated group with Yinchen Wuling Powder was 93.3%.And that of the control group with Gynostemma pentophyllum capsule was 86.7%. The result revealed that significant difference existed between the above-mentioned two groups (P < 0 . 01). According to the animal experiment,on both prevention and treatment, this recipe could inhibit the increase of the hyperlipemia model rat’s serum TCh, TG,LDL-C and the ratio of LDL-C/HDL-C (p < 0 . 01).Besides, this recipe had the effect of marked antioxidation. It could reduce the level of peroxidative lipids, and strengthen the glutathion peroxidase activities. |
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