黄惠勇,朱文锋,李冰星.调节肽与冠心病心绞痛患者中医辨证的关系[J].中国中西医结合杂志,1996,(8):474-476 |
调节肽与冠心病心绞痛患者中医辨证的关系 |
Relations of Regulatory Polypeptide and Syndrome Differentiation of Traditional Chinese Medicine of Angina Pectoris Patients |
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DOI: |
中文关键词: 调节肽 冠心病心绞痛 中医辨证学 |
英文关键词:regulatory polypeptide angina pectoris the Syndrome Differentiation of traditional Chinese medicne |
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中文摘要: |
对90例不同证型冠心病心绞痛患者血浆心钠素(ANP)、β-内啡肽(β-EP)、内皮素(ET)、血管紧张素Ⅱ(A-Ⅱ)等调节肽指标进行临床检测,结果与30例正常人比较,均有显著性差异(P<0.05,P<0.01)。且舒血管作用的ANP和β-EP检测结果呈现心气虚证组>心脉瘀阻证组>正常人组>心阴虚证组,且实验观察组3组间两两比较,均有显著性差异(P<0.01)。而缩血管作用的ET、A-Ⅱ检测结果则呈现心阴虚证组>心脉瘀阻证组>正常人组>心气虚证组,且实验观察组3组间两两比较,均有显著性差异(P<0.01)。提示ANP、β-EP、ET、A-Ⅱ等调节肽是冠心病心绞痛临床辨证的主要物质基础之一,似可作为客观化辨证的特异性指标。 |
英文摘要: |
Ninety cases of angina pectoris patients with the Deficiency of Heart Qi Syndrome(DHQS),Deficiency of Heart-Yin Syndrome(DHYS) and blood stasis in Heart vessels Syndrome(BSHVS)were studied. The number of patients were 30 for each group. Their regulatory polypeptides:atrial natri-uretic polypeptide(ANP),β-Endorphine(β-EP),Endothelin(ET),Angiotensin (A-Ⅱ) weretested. Results showed that in comparing with normal level,p <0 . 05 or<0 . 01, ANP and -βEP of them:DHQS> BSHVS>normal group> DHYS. ET and A-Ⅱ of them:DHYS> BSHVS>normal group > DHQS,And the comparison between groups revealed that P < 0 . 05 or < 0 . 0 1 . So ANP,β-EP,ET and A-Ⅱ were the principal material basis, and they could be the specific objective parameters of the Syndrome Differentiation. |
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