金水六君煎口服液治疗慢性支气管炎的临床及实验研究

目的：为了解金水六君煎扶正与祛痰的作用机理。方法：用金水六君煎治疗脾、肺、肾虚之咳、喘及痰证患者４１例，对该方进行了扶正与祛痰方面的研究。结果：金水六君煎可改善人体免疫功能及肺通气功能；增加大白鼠气管毛细管排痰量，加快家鸽气管纤毛运动速度，金水六君煎高、低剂量组实验动物与同一实验中生理盐水组比较均有显著性差异（Ｐ＜０．０１）。结论：金水六君煎有良好的祛痰作用，并可改善人体的免疫功能及肺通气功能状态。

英文摘要:

Objective: To assess the effect of Jinshui Liu inn decoction (JSL) in treating chronic bronchitis.Methods: The effect of JSL on expelling the phlegm and strengthening the body resistance were observed. Results: JSL was proved to be efficacious in improving immune function of the body and pul-monary ventilatory function (P<0.01 ). JSL could not only increase the secretion of rats’ trachea mucosa and dilute sputum, but also increase the motion speed of the pigeons’ trachea cilia, thus facilitate the removal of sputum. Compered with the normal saline control group, both animal experiments displayed significant statistical difference (P<0.01), but without significant difference when compared the JSL group with the positive drug Juhong Tanke Ye control group. Conclusion: JSL has the effect of resolving phlegm as well as improving human immunological and pulmonary ventilatory functions.

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