升白快煎剂治疗白细胞减少症临床疗效观察

作者	单位
谭达人	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008
谢兆霞	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008
钟美佐	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008
舒毅刚	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008
何群	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008
梁新文	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008
秦群	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008
谭桂山	Tan Daren, Xie Zhaoxia, Zhong Meizuo, et al Affiliated Xianya Hospital, Hunan Medical University, Changsha (410008

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中文摘要:

目的 :研究开发经口服途径作用快、药效高的升白细胞新药。方法 :将 90例血液恶性疾病化疗后白细胞减少患者分为 3组 ,即升白快煎剂观察组、升白安片对照组和空白组进行疗效观察和对比。并对 2 5例非化疗组患者进行用药前后和 3周后观察。结果 :观察组白细胞 (WBC)计数、中性粒细胞 (ANC)计数治疗后和两周后较对照组、空白组增高 (均P <0 0 1 )。观察组两周后显效率为 60 0 %、总有效率为 80 0 % ,与对照组、空白组的疗效相比有显著性差异 (均P <0 0 0 1 )。 2 5例非化疗组患者治疗后、3周后WBC、ANC较治疗前明显增加(均P <0 0 0 1 ) ,3周后显效率为 64 0 % ,总有效率为 80 0 %。结论 :初步证明升白快煎剂的升白细胞作用具有疗效较高、作用快、疗效确切和无明显副作用等特点。

英文摘要:

Objective: To study the effective orally taken medicine in treating the leukopenia. Methods: ninety cases of leukopenia induced by chemotherapy were divided into 3 groups. They were test group treated with Shengbaikuai Decoction (SBK), control group and blank group. Their efficacies were compared with each other, 25 cases with nonchemotherapy were also observed. Results: WBC count and absolute neutrophil count (ANC) in test group were higher than those of other groups immediately after treatment and 2 weeks later (P<0 01). The marked effective rate and total effective rate of test group after 2 weeks were 60.0% and 80.0% (P<0 001) respectively, which were significantly higher than those of other groups. WBC and ANC count after treatment and 3 weeks later were higher than those before treatment in nonchemotherapy group (P<0 001). The marked effective rate and total effective rate 3 weeks later were 64.0% and 80.0% respectively. Conclusions: SBK could increase WBC count rapidly and definitely without apparent side effect.

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