功能性消化不良胃排空时间测定及胃回归煎剂对其疗效研究

Determination of Gastric Emptying Time of Functional Dyspepsia and Clinical Study on Therapeutic Effect of Weihuigui Decoction on Functional Dyspepsia

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DOI：

中文关键词: 功能性消化不良胃排空时间胃回归煎剂

英文关键词:functional dyspepsia gastric emptying time Weihuigui Decoction

基金项目:

作者	单位
谷中红	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000
王先银	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000
王巧云	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000
张天成	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000
孔鸣	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000
辛国庆	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000
江秀云	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000
郑惠萍	Gu Zhonghong, Wang Xianyin, Wang Qiaoyun, et al The 520 Hospital of PLA, Mianyang, Sichuan (621000

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中文摘要:

目的 :观察功能性消化不良 (FD)患者胃排空时间及中药胃回归煎剂对其疗效。方法 :对 2 0名健康者和 64例FD患者 ,应用实时超声显像法进行胃排空时间测定。受试者空腹、饮水后 0、1 0、2 0、3 0、40、5 0min测定胃窦面积和胃体 -底交界区前后壁切面内径 ,测定胃起始收缩时间和 2min收缩次数 ;从FD组中随机选择 2 0例患者给予中药胃回归煎剂治疗 ,每次1 0 0ml,1日 3次 ,连服 2周 ,观察胃排空及临床症状改善情况。结果 :64例FD患者中有 66%存在胃液体排空延迟 ,且与胃起始收缩时间和 2min收缩次数相关。中药胃回归煎剂可改善 2 0例FD患者的胃排空时间及临床症状。结论 :FD发病确与胃动力障碍有关 ,中药胃回归煎剂治疗FD有显著疗效。

英文摘要:

Objective: To observe the gastric emptying time (GET) of and the therapeutic effect of Weihuigui Decoction (WHGD) upon functional dyspepsia (FD). Methods: GET of 64 FD patients and 20 healthy volunteers was measured by real time ultrasonography. The measurements were performed at fasting, 0,10,20,30,40 and 50 min after drinking water, the area of gastric antrum, internal diameter of the section of anterior posterior walls in corpus ventriculi fundus junction region, intitating time of gastric contraction and contractive times in 2 min were recorded. Twenty patients selected randomly were treated with WHGD 100 ml, three a day, for 2 weeks consecutively, to observe the improvement of clinical effect and gastric emptying. Results: GET was delayed in 66% of 64 FD patients as compared with that of control, and it was related with gastric contraction initiating time and contraction times in 2 min. WHGD could improve the clinical symptoms and GET of FD patients. Conclusion: WHGD has obvious therapeutic effect in treating FD.

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