| 巫刚,邹才华,毛兵,蒋俊明,黄宗文,徐杰军.急性胰腺炎患者血浆内皮素和一氧化氮变化与血瘀证关系的探讨[J].中国中西医结合杂志,1999,(12):715-717 |
| 急性胰腺炎患者血浆内皮素和一氧化氮变化与血瘀证关系的探讨 |
| Clinical Study on Relationship of Blood Stasis Syndrome with Plasma Endothelin and Nitric Oxide Changes in Acute Pancreatitis Patients |
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| DOI： |
| 中文关键词: 急性胰腺炎 血瘀证 内皮素 一氧化氮 |
| 英文关键词:acute pancreatitis blood stasis Syndrome endothelin nitric oxide |
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| 中文摘要: |
| 目的:探讨急性胰腺炎患者血浆总内皮素(ET)和一氧化氮(NO)与中医血瘀证的关系。方法:设健康人对照组和中医各证型组。采用放免法和反相高效液相色谱测定法分别检测中医各证型组治疗前后血浆ET和亚硝酸盐与硝酸盐(以亚硝酸盐与硝酸盐之和来代表NO水平)。结果:ET及ET/NO在肝脾气滞型无明显变化;在肝脾湿热血瘀型和脾胃实热血瘀型显著增高(P<005或P<001)。结论:ET增高及ET/NO比值增高可能是急性胰腺炎时存在血瘀证的重要客观指标之一。 |
| 英文摘要: |
| Objective: To study the relationship of blood stasis Syndrome with plasma endothelin (ET) and nitric oxide (NO) in acute pancreatitis patients. Methods: A healthy control group and three groups of patients with three different Syndromes of TCM were established. Patients′ ET and NO were determined by radioimmunoassay and reversed phase high performance liquid chromatography respectively before and after treatment. The NO level was represented by the sum of NO 2 and NO 3. Results: ET and ET/NO ratio were not changed significantly in patients with Liver Spleen Qi Stagnant Syndrome, but increased significantly in patients with Liver Spleen Damp Heat Syndrome or with Spleen Stomach excessive Heat Syndrome (P<0 05 or P<0 01). Conclusion: ET and ET/NO ratio might be the important objective markers of the existance of blood stasis Syndrome in acute pancreatitis patients. |
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