调激宁冲剂配合激素治疗小儿原发性肾病综合征临床观察

作者	单位
李荣辉	中国中医研究院西苑医院!北京100091
彭征屏	中国中医研究院西苑医院!北京100091
魏佑莲	中国中医研究院西苑医院!北京100091
冀晓华	中国中医研究院西苑医院!北京100091

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中文摘要:

目的:研究调激宁冲剂配合激素治疗小儿原发性肾病综合征的作用。方法:选择60例住院患儿,随机分为两组,治疗组30例用调激宁冲剂配合激素,对照组30例单用激素,疗程均为8周。观察治疗前后尿蛋白、血清白蛋白、总胆固醇、血小板及血压的变化。结果:治疗组总有效率、完全效应率明显高于对照组(P<001),尿蛋白转阴时间明显缩短(P<005)。与对照组比较,在降低血脂、血小板、预防高血压方面亦优于对照组(P<001)。结论:调激宁冲剂能增强激素治疗小儿原发性肾病综合征的疗效,并减轻其副作用,此法安全、有效,值得推广。

英文摘要:

To investigate the effects of Tiaojining recipe (TJNR) combined with corticosterone (CS) in treating infantile primary nephrotic syndrome (IPNS). Methods: Sixty inpatients with IPNS were divided into two groups, which consisted of 30 cases as the treated group treated by TJNR combined with CS and 30 cases of the control group were treated by CS alone for 8 weeks. The changes of urinary protein, serum albumin, blood cholesterol, platelet and blood pressure before and after treatment were observed. Results: The total effective rate of the treated group was significantly higher than that of the control group (P<0 01). The times for urinary protein disappearance of the treated group was significantly shorter than that of the control group (P<0 05). Compared with the control group. TINR could prevent hypertension, lower lipidemia and platelets (P<0 01). Conclusion: TJNR could enhance the curative effects of CS on IPNS and reduce the side effects of CS safely and effectively.

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