洁童阴洗液治疗幼女外阴阴道炎的临床与实验研究

作者	单位
刘慧丽	首都医科大学附属北京儿童医院北京100045
柳静	首都医科大学附属北京儿童医院北京100045
陈昭定	首都医科大学附属北京儿童医院北京100045

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中文摘要:

目的 :探讨中药洁童阴洗液治疗幼女外阴阴道炎的临床疗效和作用机理。方法 :随机设洁童阴洗液观察组 (简称观察组 ) 30 0例和日舒安洗液对照组 (简称对照组 ) 6 0例 ,对两组患儿治疗前后主要症状和体征积分值进行对比观察 ,并进行中药药理药效学的动物实验。结果 :临床总有效率观察组与对照组分别为 98%和 93% ,治愈率分别为 93%和 83% ,观察组治愈率明显优于对照组 (P <0 0 5 )。实验研究表明 ,该制剂具有抗炎、抑菌、止痒、镇痛、调节免疫功能的作用 ,且对粘膜无刺激。结论 :洁童阴洗液治疗幼女外阴阴道炎具有良好可靠的疗效 ,它具有抗炎、抑菌、止痒、镇痛、调节免疫功能的作用 ,且无明显的不良反应。

英文摘要:

Objective: To study the clinical effect and mechanism of Jietongyin Lotion (JTYL) in treating vulvovaginitis in young girls. Methods: Patients were randomized into the JTYL group (n=300) and the control group (n=60, treated with Rishu′an Lotion). Comparative observation on scoring of main symptoms and signs in them was carried out, and the pharmacological and pharmacodynamic experiment was also conducted on effect of JTYL in animals. Results: In the JTYL group, the total effective rate was 98% and was 93% in the control group. The cure rate in the two groups was 93% and 83% respectively, which was significantly higher in the JTYL group (P<0 05). Experimental study showed that JTYL has effects in anti inflammation, bacteriocidal, itching relieving, pain releasing, and immune regulation. It showed non irritatory on mucous membrane. Conclusion: JTYL has good reliable effect in treating vulvovaginitis in young girls without any obvious adverse effects, showing anti inflammatory, bacteriocidal, itching relieving, pain releasing and immune regulation

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