丹蒲胶囊对大鼠细菌性前列腺炎病理模型的影响

作者	单位
卢建新	中国中医研究院广安门医院泌尿外科北京 100053
高小松	中国中医研究院广安门医院泌尿外科北京 100053
孔令青	中国中医研究院广安门医院泌尿外科北京 100053
庞然	中国中医研究院广安门医院泌尿外科北京 100053
郭军	中国中医研究院广安门医院泌尿外科北京 100053
张亚强	中国中医研究院广安门医院泌尿外科北京 100053

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中文摘要:

目的:探讨纯中药制剂丹蒲胶囊治疗细菌性前列腺炎的作用机制。方法:将标准大肠杆菌0.2ml注射至大鼠前列腺腹侧叶,造成细菌性前列腺炎病理模型,同时应用丹蒲胶囊治疗,观察对病理模型的影响。结果:光学显微镜显示模型大鼠前列腺间质炎细胞浸润及纤维组织增生明显,丹蒲胶囊组大鼠前列腺间质炎细胞浸润及纤维组织增生程度均轻于对照组。结论:丹蒲胶囊具有修复前列腺组织,减轻病变前列腺间质炎症反应和纤维组织增生作用。

英文摘要:

Objective: To investigate the mechanism of Danpu Capsule (DPC) in treating bacterial prostatitis. Methods: The pathological model of bacterial prostatitis was established by injecting 0.2 ml of standard E. Coli in the ventral lobe of rat’s prostate, and the model was treated with DPC to observe its effect. Results: Optical microscopic examination showed obvious mesenchymal inflammatory cell infiltration and hyperplasia of fibrous tissue in prostate of model rats, but these pathological changes were reduced after treatment of DPC. Conclusion: DPC has the effects of repairing prostatic tissue, alleviating mesenchymal inflammatory reaction and hyperplasia of fibrous tissue.

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