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邓海霞,朱南孙,王采文,岑幻仙,须义贞.加味没竭片对原发性痛经患者经期血浆催产素的影响[J].中国中西医结合杂志,2003,(5):354-356
加味没竭片对原发性痛经患者经期血浆催产素的影响
Effect of Jiawei Mojie Tablet on Plasma Oxytocin Level in Patients with Primary Dysmenorrhea in Menstrual Period
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DOI:
中文关键词:  原发性痛经  催产素  加味没竭片
英文关键词:primary dysmenorrhea  oxytocin  Jiawei Mojie Tablet
基金项目:上海市卫生局中医药开发研究基金资助课题 (No.XY970 0 5)
作者单位
邓海霞 上海中医药大学附属岳阳医院妇科 上海200437 
朱南孙 上海中医药大学附属岳阳医院妇科 上海200437 
王采文 上海中医药大学附属岳阳医院妇科 上海200437 
岑幻仙 上海中医药大学附属岳阳医院妇科 上海200437 
须义贞 上海中医药大学附属岳阳医院妇科 上海200437 
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中文摘要:
      目的 :观察加味没竭片对原发性痛经患者经期血浆催产素 (oxytocin ,OT)的影响 ,探讨其治疗原发性痛经的作用机制。方法 :将原发性痛经患者 6 3例 ,随机分为加味没竭片治疗组 (加味没竭片组 ,33例 )和月月舒冲剂对照组 (月月舒组 ,30例 ) ,并设健康对照组 16名。观察治疗前后患者经期血浆OT含量变化。结果 :原发性痛经患者OT水平明显高于健康对照组 (P <0 0 1) ,患者血浆OT含量与疼痛程度呈显著正相关 (r =0 738,P <0 0 1) ;治疗后加味没竭片组OT含量显著下降 (P <0 0 1) ,优于月月舒组 (P <0 0 1)。结论 :加味没竭片能降低原发性痛经患者经期血浆催产素含量。
英文摘要:
      Objective: To investigate the therapeutic mechanism of Jiawei Mojie Tablet (JMT) in treating primary dysmenorrhea (PD) by observing its effect on plasma oxytocin (OT) level in patients in menstrual period. Methods: Sixty three patients with PD enrolled in the study were randomly divided into the JMT group (n=33) and the control Group (n=30, treated with Yueyueshu Granule) to observe the change of OT level in the menstrual period before and after treatment. Results: OT level in patients with PD was obviously higher than that in healthy subjects (P<0 01), and was positively correlated with the degree of pain (r=0.738, P<0 01). OT level reduced significantly after treatment (P<0 01), the reduction was more significant in the JMT group than that in the control group (P<0 01). Conclusion: JMT could reduce the OT level in menstrual period.
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