| 胡岳然,吴超权,刘雅洁,王耀邦,李先明,钟鹤立,余玉娇.参芪放后方防治头颈部肿瘤放射损伤的疗效观察[J].中国中西医结合杂志,2005,(7):623-625 |
| 参芪放后方防治头颈部肿瘤放射损伤的疗效观察 |
| Clinical Observation on Effect of Shenqi Fanghou Recipe in Preventing and Treating Radiation Injury in Patients with Head and Neck Tumor |
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| DOI： |
| 中文关键词: 参芪放后方 头颈部肿瘤 放射损伤 |
| 英文关键词:Shenqi Fanghou recipe head and neck tumor radiation injury |
| 基金项目:深圳市科技局资助课题(No.200204022) |
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| 中文摘要: |
| 目的观察自拟参芪放后方防治头颈部肿瘤放射损伤的疗效。方法将140例头颈部肿瘤(鼻咽癌、扁桃体癌、舌癌)患者随机分成两组,观察组(70例)放疗期间服用参芪放后方加减,对照组(70例)单纯放疗,同时观察两组患者放疗过程中放射反应及晚期放射损伤情况。结果观察组在放疗期间口咽黏膜反应、口干程度、颈部放射性皮炎程度均较轻;晚期患者放射后遗症如张口受限度、颈部肌肉硬化程度观察组均比对照组轻,两组比较差异有显著性(P<0.01)。结论参芪放后方有防治头颈部肿瘤放射反应及晚期放射损伤的作用。 |
| 英文摘要: |
| ObjectiveTo observe the therapeutic effect of Shenqi Fanghou recipe (SFR) in preventing and treating radiation injury in patients with head and neck tumor. MethodsOne hundred and forty patients with head and neck tumor, including nasopharyngeal carcinoma, carcinoma of tonsil or tongue, were randomly divided into 2 groups, 70 patients in the observed group were given modified SFR as adjuvant to radiotherapy, while 70 patients in the control group were treated with radiotherapy alone. The radiation reactions during radiotherapy and the condition of late stage radiation injury radiotherapy in patients in the 2 groups were observed. ResultsThe degree of oropharyngeal mucosa reaction, dryness in mouth and radiation dermatitis in cervical region in the observed group was milder than those in the control group, and the radiation injury induced late stage sequelae, such as the degree of mouth-opening was better and the cervical muscular sclerosis was better in the observed group than in the control group, showing significant difference (P<0.01). ConclusionSFR has definite effect in preventing and treating radiation reaction and late stage radiation injury in patients with head and neck tumor. |
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