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倪敬年,时晶,刘炳林,刘建平,田金洲.中药治疗痴呆临床试验中证候结局的评价[J].中国中西医结合杂志,2013,33(3):404-407
中药治疗痴呆临床试验中证候结局的评价
Assessment of the Results of Syndrome in Clinical Trials of Dementia Treated by Chinese Herbal Medicine
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DOI:
中文关键词:  证候  证候量表  痴呆  结局评价
英文关键词:syndrome  syndrome scale  dementia  outcome assessment
基金项目:国家重大新药创制平台建设项目[No.2011ZX09302-006-01-03(4)];北京中医药大学神经变性病创新团队(No. 2011-CXTD-21)
作者单位E-mail
倪敬年,时晶,刘炳林,刘建平   
田金洲 北京中医药大学东直门医院脑病三区(北京 100700) jztian@hotmail.com 
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中文摘要:
      证候疗效作为次要疗效指标已经在中药治疗痴呆的临床试验中广泛使用,证候评估工具是证候疗效评价的关键,目前的痴呆证候评估工具有待进一步完善,包括内容设计、信度和效度评价等。笔者以中医学理论为基础,结合量表开发的共性要求,对证候评估量表设计相关的问题进行了述评。
英文摘要:
      Chinese medical syndrome efficacy, as a second efficacy indicator, has been widely used in clinical trials of treating dementia by Chinese herbal medicine. The syndrome assessment tool is a key point in assessing the efficacy of Chinese medical syndrome. The syndrome assessment tool for dementia used nowadays needs to be optimized in content, reliability, and validity. In this paper, the authors reviewed some problems correlated with the design of Chinese medical assessment questionnaire on the basis of Chinese medical theories by combining the common requirements for questionnaire development.
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